Mounjaro Weight Loss Success Stories
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Weight loss through injections - a topic on everyone's lips and for a good reason. As an increasing amount of people turn to the drug and see great results its popularity is increasing and scaled production has made Mounjaro, with the active substance tirzepatide, widely available to the public. In this article, we will look at the proven results through clinical trials and compare them to real-life experiences to give you an idea of what you can expect and help you make an informed decision if Mounjaro is for you.
The clinical trials
Eli Lilly, the company behind Mounjaro presented clinical trials with the following results:
Overall Weight Loss
- 21.1% mean weight loss after the 12-week intensive lifestyle intervention lead-in period.
- A total mean weight loss of 26.6% (29.2 kg or 64.4 lb.) from study entry over 84 weeks.
Comparison to Placebo
- Tirzepatide group: 26.6% total mean weight loss
- Placebo group: 3.8% total mean weight loss (4.1 kg or 9.0 lb.) from study entry over 84 weeks
The trial results showed:
- 87.5% of participants on tirzepatide achieved ≥5% weight reduction
- 44.7% of participants on tirzepatide achieved ≥20% weight reduction
View the entire clinical trial press release and documentation.
What does a 21.1% weight loss look like?
The following table shows what can be achieved based on the 21.1% mean weight loss in the clinical trial. Please note that actual results may vary and that although the clinical trials spanned across 12 weeks some patients find the medications work faster and some slower.
| Starting weight (kg) | Weight Loss (kg) | New weight (kg) |
|---|---|---|
| 60.0 | 12.7 | 47.3 |
| 65.0 | 13.7 | 51.3 |
| 70.0 | 14.8 | 55.2 |
| 75.0 | 15.8 | 59.2 |
| 80.0 | 16.9 | 63.1 |
| 85.0 | 17.9 | 67.1 |
| 90.0 | 19.0 | 71.0 |
| 95.0 | 20.0 | 75.0 |
| 100.0 | 21.1 | 78.9 |
| 105.0 | 22.2 | 82.8 |
| 110.0 | 23.2 | 86.8 |
| 115.0 | 24.3 | 90.7 |
| 120.0 | 25.3 | 94.7 |
| 125.0 | 26.4 | 98.6 |
| 130.0 | 27.4 | 102.6 |
| 135.0 | 28.5 | 106.5 |
| 140.0 | 29.5 | 110.5 |
Patient reviews
Now let's look at some patient reviews and how they describe their experiences. Please note that these have been selected to highlight positive experiences taking Mounjaro. If you are interested in learning more about side effects, please see our article on common side effects when taking Mounjaro.
Anchy (October 9, 2024):
Anchy describes Mounjaro as a "Life changer!" Over a span of 6 months to 1 year, this 36-year-old female, standing at 5’9’’, went from 220 lbs to losing 42 lbs by mid-October 2024. She is close to reaching her final goal of 165 lbs, a weight she hasn't seen since her mid-twenties. Anchy emphasizes that she "literally looks better now compared to [her] 26." Beyond physical appearance, she notes significant improvements in her health and general mental attitude, stating, "Not to mention how my health improved and general mental attitude." Remarkably, she experienced zero side effects. Despite acknowledging the treatment is pricey, she believes it's worth every penny because nothing else had worked for her before.
Sushi (September 18, 2024):
Sushi had an "amazing" experience with Mounjaro over a period of 1 to 2 years. She lost 25 lbs in just one month by combining the medication with healthy eating. Sushi highlights that she no longer needs blood pressure medication or statins, indicating significant health improvements. Impressively, she has maintained her weight loss for a year using a maintenance dose of 5 mg once a month. She reports "zero negative side effects," which contributed to her positive experience. Sushi's journey showcases how Mounjaro can lead to rapid weight loss and long-term weight maintenance when coupled with a healthy lifestyle.
Penny (September 11, 2024):
Penny, a 50-year-old, shares that she has "not had any side effects and has lost around 70 lbs" while using Mounjaro for 6 months to 1 year. She expresses that she feels better now than she has in years, emphasizing the positive impact on her overall well-being. "I feel better than I have in years, and I'm 50 years old," she notes. Penny's experience highlights significant weight loss without adverse effects, leading to improved health and vitality at midlife.
Kat (September 3, 2024):
Kat reports a highly positive experience with Mounjaro over 1 to 6 months. She shares, "Have lost 26 lbs in 15 weeks... I am loving Mounjaro. I’m so happy." While she occasionally struggled to eat because she didn't feel hungry, there were not many side effects. Kat highlights the medication's effectiveness in reducing appetite, which contributed to her substantial weight loss. Her overall happiness and satisfaction reflect the positive impact Mounjaro has had on her life.
Wasabe (August 25, 2024):
Wasabe, a 60-year-old male, describes Mounjaro as an "amazing drug." Over 1 to 6 months, he lost 20% of his body weight and is nearing his target weight using a 12.5 mg dose. He notes significant health improvements: "My blood pressure is now normal, triglycerides are normal, and my joints don’t ache." Wasabe did not experience any notable side effects during his treatment. His experience underscores the medication's ability to facilitate substantial weight loss and alleviate health issues related to obesity.
Sarah (August 15, 2024):
Sarah, a 55-year-old female weighing 183 lbs at 5’6, was "amazed how fast it started to work." In less than a month on the lowest dose of 2.5 mg, she lost 10 lbs in three weeks. She shares that her cravings have disappeared, and she no longer thinks about food constantly. "Cravings have gone. No longer thinking about food all the time," she says. Additionally, Sarah is sleeping better. The only side effect she mentions is slight nausea the day after the injection, which she seems to consider minor compared to the benefits she's experiencing.
Pamela (August 13, 2024):
Pamela describes Mounjaro as "life changing." Over 1 to 6 months, she reports that it "stopped the food noise in my head," allowing her to eat sensibly. As a result, she dropped a dress size in just 5 weeks. "Now eating sensibly and have dropped a dress size in 5 weeks," she notes. The significant reduction in constant thoughts about food has positively impacted her eating habits and weight loss journey.
JAS (August 12, 2024):
JAS had a great experience with Mounjaro over 1 to 6 months, stating it "works great, definitely recommend for weight loss." They lost about 30 pounds in the first month alone, highlighting the medication's effectiveness. "Lost about 30 pounds in the first month alone," they share. JAS highly recommends Mounjaro to others seeking significant weight loss results.
Conclusion - Did it live up to the hype?
The analysed reviews are similar to the clinical trial results presented by Eli Lilly. Both the reviews and the trials show that Mounjaro helps people lose a significant amount of weight — often around 20% or more of their starting weight. Positive effects such as improved health markers, reduced appetite, and few side effects mentioned in the reviews match the positive outcomes seen in the clinical trials. Differences include the time frames and individual experiences; some reviewers lost significant weight in shorter periods than the 84-week clinical trial, and there were variations in side effects and weight loss rates among individuals. Overall, the reviewers' experiences are consistent with the clinical trial findings, showing that Mounjaro effectively aids in weight loss with generally manageable side effects.
Sources:
Drugs.com - Mounjaro patient Reviews
