Orlos 60mg 84 Capsules is a weight-loss aid for adults with a BMI of 28 or higher. It works by reducing fat absorption, helping you lose extra weight compared to dieting alone. When combined with a low-fat diet and exercise, Orlos can improve weight-loss results. This non-prescription medication contains orlistat, proven effective for weight control.

Key Features:

• Fat blocker: Reduces about 25% of dietary fat absorption
• Clinically proven: Helps lose up to 50% more weight than diet alone
• Easy to use: Take one capsule with each main meal
• Suitable for: Adults with a BMI of 28 or more
• Dosage: 84 capsules provide a 4-week supply
• Complementary: Works best with a low-fat, calorie-reduced diet

How long can I take Orlos for?

Orlos may be used for up to six months. If no weight loss occurs after 12 weeks, consult a doctor.

Are there any side effects?

Some users might experience mild digestive discomfort. Reducing dietary fat intake can help manage these effects.

Do I need a prescription for Orlos?

No, Orlos 60mg is available over-the-counter without needing a prescription.

Patient Information Leaflet

The active substance is orlistat. Each hard capsule contains 60 mg of orlistat.

The other ingredients are: capsule filing microcrystalline cellulose (E460), sodium starch glycolate (type A), sillica colloidal anhydrous, sodium laurilsulfate capsule shell gelatin, titanium dioxide (E171), indigo carmine (E132).

Always take this medicine exactly as described in the Patient Information Leaflet or as your doctor or pharmacist have told you. Check with your doctor or pharmacist if you are not sure.

Adults 18 and over

The recommended dose is:

• Take one capsule, three times a day.
• Take Orlos just before, during or up to one hour after meals. This usually means one capsule at breakfast, lunch and dinner. Make sure your three main meals are well balanced, reduced calorie, and lower-fat.
• If you miss a meal, or your meal contains no fat, do not take a capsule. Orlos does not work unless there is some fat in the meal
• Swallow the capsule whole with water.
• Do not take more than 3 capsules a day.
• Eat lower-fat meals to reduce the chance of diet-related treatment effects.
• Try to be more physically active before you start taking the capsules. Physical activity is an important part of a weight loss programme. Remember to check with your doctor first if you have not exercised before.
• Continue to be active while taking Orlos and after you stop taking it

How long should Orlos be taken

• Orlos should not be taken for more than six months.If you do not lose weight after taking Orlos for 12 weeks, see your doctor or pharmacist for advice. You may need to stop taking Orlos Capsules.
• Successful weight loss is not just about eating differently for a short period of time before reverting to your old habits. People who lose weight and maintain the loss make lifestyle changes, which include changes to what they eat and how active they are.

If you take more Orlos than you should Do not take more than 3 capsules a day. If you have taken too many capsules, contact a doctor as soon as possible.

If you forget to take Orlos If you miss taking a capsule:

• If it is less than an hour since your last main meal, take the missed capsule
• If it is more than an hour since your last main meal, do not take the missed capsule. Walt and take the next capsule around your next main meal as usual.Do not take a double dose to make up for a forgotten dose.

If you stop taking Orlos

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Do not take Orlos:

• If you are allergic to orlistat or any of the ingredients of this medicine
• If you are pregnant or breast-feeding
• If you are taking ciclosporin, used after organ transplants, for severe rheumatoid arthritis and some severe skin conditions - If you are taking warfarin or other medicines used to thin the blood
• If you are allergic (hypersensitive) to orlistat or any of the ingredients of Orlos
• If you have cholestasis (condition where the flow of bile from the liver is blocked)
• If you have problems absorbing food (chronic malabsorption syndrome) diagnosed by a doctor.

Talk to your doctor or pharmacist before taking Orlos:

• If you have diabetes. Tell your doctor who may need to adjust your anti-diabetic medicine.
• If you have kidney disease. Talk to your doctor before taking Orlos if you have problems with your kidneys. The use of Orlos may be associated with kidney stones in patients suffering from chronic kidney disease.

Children and adolescents

This medicine must not be taken by children and adolescents under 18 years old.

Other medicines and Orlos

Orlos may affect some medicines you have to take. Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.

Do not take Orlos with these medicines:

• ciclosporin ciclosporin is used after organ transplants, for severe rheumatoid arthritis and some severe skin conditions.
• Warfarin or other medicines used to thin the blood.
• Acarbose (an anti-diabetic drug used to treat type 2 diabetes mellitus). Orlos is not recommended for people taking Acarbose.

The oral contraceptive pill and Orlos 60 mg Capsules

The oral contraceptive pill may be less effective if you get severe diarrhoea. Use an extra method of contraception if you get severe diarrhoea.

Multivitamins and Oros 60 mg Capsules

You should take a multivitamin, every day. Orlos can lower the levels of some vitamins absorbed by your body. The multivitamin should contain vitamins A, D, E and K. You should take the multivitamin at bedtime, when you will not be taking Orlos, to help ensure that the vitamins are absorbed.

Talk to your doctor or pharmacist before taking Orlos if you are taking:

• amiodarone, used for heart rhythm problems;
• acarbose, (an anti-diabetic drug used to treat type 2 diabetes mellitus). Orlos is not recommended for people taking acarbose.
• a thyroid medicine (levothyroxine) as it may be necessary to adjust your dose and take your medicines at different times of the day.
• a medicine for epilepsy as any changes in the frequency and severity of your convulsions should be discussed with your doctor.
• medicines to treat HIV. It is important that you consult your doctor before taking Orlos if you are receiving treatment for HIV.
• medicines for depression, psychiatric disorders or anxiousness. It is important that you consult your doctor before taking Orlistat if you are receiving treatment for depression, mood or anxiety disorders.

Talk to your doctor or pharmacist when taking Orlos

• if you are taking a medicine for high blood pressure as it may be necessary to adjust your dose;
• you are taking a medicine for high cholesterol as it may be necessary to adjust your dose.

Orlos with food and drink

Orlos should be used along with a reduced calorie, lower-fat diet. Try to start this diet before beginning treatment. For information on how to set your calorie and fat targets, see the Patient Information Leaflet.

Pregnancy, breast-feeding and fertility

Do not take Orlos if you are pregnant or breast-feeding. Studies do not indicate harmful effects with respect to fertility.

Driving and using machines

No effect on ability to drive or use machines has been observed.

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Most of the common side effects related to Orlos Capsules (for example, wind with or without oily spotting, sudden or more frequent bowel motions and soft stools) are caused by the way it works. Eat lower-fat meals to help manage these diet-related treatment effects.

Serious side effects (it is not known how frequently these side effects occur)

Severe allergic reactions:

• Signs of a severe allergic reaction include: severe breathing difficulties, sweating, rash, itching, swollen face, rapid heartbeat, collapse.

Stop taking the Orlos. Get medical help immediately.

Other serious side effects

• Bleeding from the back passage (rectum)Diverticulitis (inflammation of the large intestine). Symptoms may include lower stomach (abdominal) pain, particularly on the left side, possibly with fever and constipation.
• Pancreatitis (inflammation of the pancreas). Symptoms may include severe abdominal pain sometimes radiating towards the back, possibly with fever, nausea and vomiting
• Skin blistering (including blisters that burst)
• Severe stomach pain caused by gallstones
• Hepatitis (inflammation of the liver). Symptoms can include yellowing skin and eyes, itching, dark coloured urine, stomach pain and liver tenderness (indicated by pain under the front of the rib cage on your right hand side). sometimes with loss of appetite.
• Oxalate nephropathy (build up of calcium oxalate which may lead to kidney stones).

Stop taking the capsules. Tell your doctor if you get any of these.

Very common side effects (may affect more than 1 in 10 people)

• Wind (fatulence), with or without oily spotting
• Sudden bowel motions
• Oly discharge, fatty or oily stools
• Soft stools

Tell your doctor or pharmacist if any of these side effects gets severe or troublesome.

Common side effects (may affect up to 1 in 10 people)

• Stomach (abdominal) pain
• Incontinence (stools)
• Runny liquid stools
• More frequent bowel motions
• Anxiety

Tell your doctor or pharmacist if any of these side effects gets severe or troublesome.

Effects seen in blood tests (it is not known how frequently these effects occur)

• Increases in the levels of some liver enzymes
• Effects on blood clotting in people taking warfarin or other blood-thinning (anti-coagulant) medicines.

Tell your doctor that you are taking Orlos when you have a blood test.

If any of the side effects become serious, or if you notice any side effects not listed, tell your doctor or pharmacist.