Dovonex Ointment is a prescription medicine used to treat plaque psoriasis in adults. It contains calcipotriol, a vitamin D analogue that helps regulate skin cell growth. The ointment is recommended for use in adults and children from the age of 6.

Key Features

Features calcipotriol, a vitamin D3 derivative
Address plaque psoriasis in grown-ups
Balances skin cell growth for symptom relief
Established efficacy with good tolerance
Applied directly to the affected area
Being a prescription medication ensures expert oversight

How much time does Dovonex typically need to show results?

Most patients have observed the safety and effectiveness of Dovonex Ointment within an eight-week span. Yet, results can vary among individuals, making it crucial to heed healthcare providers' usage directions.

Is the facial application of Dovonex Ointment safe?

Applying Dovonex Ointment on the face is generally not advised due to potential skin irritation. Ensuring proper application and washing hands afterwards can prevent the unintended transfer to the face and eyes.

Can Dovonex Ointment be used for extended periods?

Over 400 patients underwent open-label clinical Dovonex Ointment trials for up to a year. Regardless, always adhere to healthcare providers' advice and usage recommendations.

Please note

This treatment is available only after a consultation with our pharmacist via a private service, called PGD (Patient Group Direction).

A picture of the affected area may facilitate and speed up the processing of your order. This can be sent to pharmacy@medino.com before or after you place the order.

It might be necessary to confirm the identity of the intended user through a verification process.

Please read the Patient information leaflet before starting the treatment.

Ingredients

Active Ingredient: 1 gram contains 50 micrograms of calcipotriol.

Excipient(s) with known effect: Propylene glycol

Read the patient leaflet for the full list of ingredients.

Usage and Instructions

Apply a thin layer to the affected skin twice a day. Leave it on the skin all day/night before bathing/showering. Wash your hands before/after use. Avoid sunlight exposure. Adults: Do not use more than 100 grams weekly. Children over 12 years: Do not use more than 75 grams weekly. Children aged 6 to 12 years: Do not use more than 50 grams weekly.

Warnings

Effects on Calcium Metabolism: Exceeding the maximum weekly dose of Dovonex may lead to hypercalcaemia due to its calcipotriol content, which is of concern, especially in certain psoriasis types. Serum calcium levels return to normal when treatment is stopped. Following dosage recommendations minimizes the risk. This product is contraindicated in patients with known disorders of calcium metabolism.

Local Adverse Reactions: Avoid applying Dovonex® to the face as it can cause skin irritation. Proper application and hand washing are crucial to prevent accidental transfer to the face and eyes.

UV Exposure: Patients on Dovonex Ointment should limit sun exposure. The use of Dovonex with UV radiation should only occur if potential benefits outweigh the risks, with physician guidance.

Unevaluated Use: Dovonex should be avoided in certain psoriasis types (guttate, erythrodermic, exfoliative, pustular) due to limited data. It should also be avoided in severe liver and kidney disease patients.

Adverse Reactions to Excipients: Dovonex®* ointment contains propylene glycol, which may cause skin irritation as an excipient.

Fire Hazard: Patients using Dovonex should not smoke or be near open flames, as the product makes fabric more flammable. Washing clothing and bedding may reduce but not entirely remove the product build-up.

Contraindicated in pregnancy and breastfeeding.

Side Effects

Category	Frequency	Adverse Effects
Infections and Infestations	Uncommon (≥1/1,000 to <1/100)	Folliculitis
Immune System Disorders	Rare (≥1/10,000 to <1/1,000)	Hypersensitivity
Metabolism and Nutrition Disorders	Rare (≥1/10,000 to <1/1,000)	Hypercalcaemia
Skin and Subcutaneous Tissue Disorders	Common (≥1/100 to <1/10)	Psoriasis aggravated
		Dermatitis
		Erythema
		Skin exfoliation
		Skin burning sensation
		Skin irritation
		Pruritus
	Uncommon (≥1/1,000 to <1/100)	Rash*
		Dry skin
	Rare (≥1/10,000 to <1/1,000)	Photosensitivity reaction
		Skin oedema
		Urticaria
		Seborrhoeic dermatitis
Renal and Urinary Disorders	Rare (≥1/10,000 to <1/1,000)	Hypercalciuria
General Disorders and Administration Site Conditions	Common (≥1/100 to <1/10)	Application site pain
	Uncommon (≥1/1,000 to <1/100)	Application site pigmentation changes